Fig. 2

CHDs seen in newborn Tbx5 ^+/− trisomic and euploid mice. Coronal histological sections of wild type (a) and Ts65Dn;Tbx5 ^+/− (b–e) newborn mice stained with H&E. Overriding aorta (b), Gerbode’s defect (c), ASDs (d), and VSDs (e) were seen in the examined animals. RA/LA: right/left atrium, RV/LV: right/left ventricle