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Organogenesis and Organoids

This section considers studies in the development of all organs and tissues. This section is also expanding to include research on organoids and the latest tools developed to facilitate organoid formation. We also welcome manuscripts on the use of organoids as a tool for studying disease.

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  1. Valuable insights into the complex process of retinal vascular development can be gained using models with abnormal retinal vasculature. Two such models are the recently described mouse lines with mutations in La...

    Authors: Malia M Edwards, D Scott McLeod, Rhonda Grebe, Céline Heng, Olivier Lefebvre and Gerard A Lutty

    Citation: BMC Developmental Biology 2011 11:60

    Content type: Research article

    Published on:

  2. Sox6 is a multi-faceted transcription factor involved in the terminal differentiation of many different cell types in vertebrates. It has been suggested that in mice as well as in zebrafish Sox6 plays a role i...

    Authors: Chung-Il An, Yao Dong and Nobuko Hagiwara

    Citation: BMC Developmental Biology 2011 11:59

    Content type: Research article

    Published on:

  3. During liver development, intrahepatic bile ducts are thought to arise by a unique asymmetric mode of cholangiocyte tubulogenesis characterized by a series of remodeling stages. Moreover, in liver diseases, ce...

    Authors: Peter S Vestentoft, Peter Jelnes, Branden M Hopkinson, Ben Vainer, Kjeld Møllgård, Bjørn Quistorff and Hanne C Bisgaard

    Citation: BMC Developmental Biology 2011 11:56

    Content type: Research article

    Published on:

  4. Nkx2.2 and Arx represent key transcription factors implicated in the specification of islet cell subtypes during pancreas development. Mice deficient for Arx do not develop any alpha-cells whereas beta- and delta...

    Authors: Simon Kordowich, Patrick Collombat, Ahmed Mansouri and Palle Serup

    Citation: BMC Developmental Biology 2011 11:52

    Content type: Research article

    Published on:

  5. In a recent genomic study, Leung et al. used a factorial microarray analysis to identify Smarca4 (Brg1)-regulated genes in micro-dissected zebrafish retinas. Two hundred and fifty nine genes were grouped in th...

    Authors: Monica R Hensley, Farida Emran, Sylvia Bonilla, Liyun Zhang, Wenxuan Zhong, Paul Grosu, John E Dowling and Yuk Fai Leung

    Citation: BMC Developmental Biology 2011 11:45

    Content type: Research article

    Published on:

  6. Sphingosine-1-phosophate (S1P) is a biologically active sphingolipid metabolite that influences cellular events including differentiation, proliferation, and migration. S1P acts through five distinct cell surf...

    Authors: Ryan R Poulsen, Carolyn M McClaskey, Scott A Rivkees and Christopher C Wendler

    Citation: BMC Developmental Biology 2011 11:37

    Content type: Research article

    Published on:

  7. Paraxial protocadherin (PAPC) plays a crucial role in morphogenetic movements during gastrulation and somitogenesis in mouse, zebrafish and Xenopus. PAPC influences cell-cell adhesion mediated by C-Cadherin. A...

    Authors: Barbara Jung, Almut Köhler, Alexandra Schambony and Doris Wedlich

    Citation: BMC Developmental Biology 2011 11:36

    Content type: Research article

    Published on:

  8. The Drosophila wing represents a particularly appropriate model to investigate the developmental control of phenotypic variation. Previous studies which aimed to identify candidate genes for wing morphology demon...

    Authors: Valeria P Carreira, Ignacio M Soto, Julián Mensch and Juan J Fanara

    Citation: BMC Developmental Biology 2011 11:32

    Content type: Research article

    Published on:

BMC Developmental Biology

ISSN: 1471-213X

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